Algicidal Activity of Glycerolipids from Brown Alga Ishige sinicola toward Red Tide Microalgae

作者：Hirao Shotaro; Tara Kenji; Kuwano Kazuyoshi; Tanaka Junji; Ishibashi Fumito^*

来源：Bioscience Biotechnology and Biochemistry, 2012, 76(2): 372-374.

DOI：10.1271/bbb.110645

• algicidal compound
• Ishige sinicola
• alpha-monoglyceride
• 1-O-palmitoyl-3-O-(6-sulfo-alpha-D-quinovopyranosyl)-sn-glycerol

Bioassay-guided fractionation of a methanol extract of the brown alga, Ishige sinicola, led to the isolation of five algicidal compounds. Their structures were determined to be alpha-monoglycerides of eicosa-5Z,8Z,11Z,14Z-tetraenoic (arachidonic) acid, octadeca-6Z,9Z,12Z,15Z-tetraenoic acid, linoleic acid and oleic acid, and 1-O-palmitoyl-3-O-(6-sulfo-alpha-D-quinovopyranosyl)-sn-glycerol on the basis of spectroscopic data and a comparison with the data in the literature. These glycerolipids showed moderate-to-high cell lysis activity against the red tide microalgal species, Heterosigma akashiwo, Karenia mikimotoi and Alexandrium catenella, at a concentration of 20 mu g/mL.

• 出版日期2012-2