Using Partial Least Squares Regression to Analyze Cellular Response Data

作者：Kreeger Pamela K^*

来源：Science Signaling, 2013, 6(271): tr7.

DOI：10.1126/scisignal.2003849

• PLSR
• multivariate analysis
• systems biology
• computational biology
• cancer therapy

This Teaching Resource provides lecture notes, slides, and a problem set for a lecture introducing the mathematical concepts and interpretation of partial least squares regression (PLSR) that were part of a course entitled "Systems Biology: Mammalian Signaling Networks." PLSR is a multivariate regression technique commonly applied to analyze relationships between signaling or transcriptional data and cellular behavior.

• 出版日期2013-4-16