摘要

Dandruff is a scalp disorder affecting more than half the population and often causes itching. Dandruff may be the result of seborrheic dermatitis, eczema, psoriasis or very commonly, an overgrowth of yeast like fungus called malassezia. Dandruff might also lead to Eye problems, acne, hair loss, allergies, swollen glands, rashes and research in this area would be both objective to the present scenario and lucrative potentially. Nanoparticles are frequently in use in some very powerful antimicrobial and antifungal cosmetics. However, most metallic nanoparticles are harsh and often toxic, and concern remains on their ill effects. Sulphur, certified as biocompatible to eukaryotes and as soil nutrient is often used in medicine. Sulphur nanoparticles is a strong antifungal agent and have been used in macro amount in shampoos. This paper concentrates on synthesizing sulphur nanoparticles in a surfactant system, insitu, such that it could possibly be used in curbing dandruff naturally The objective is to Synthesize and optimize sulphur nanoparticles in surfactant CTAB, GrowM.furfur in culture and optimize its growth and to study antimicrobial activity of sulphur nanoparticles on this strain. To check its antidandruff activity, experiments have been conducted on Malassezia furfur the causal organism for seborrheaic dermatitis or dandruff, which have been cultured for such study in our lab. Toxicity of nanoparticles is of a grave concern and a lot of effort is given to study and counter its toxic effects, the toxic nature itself serves a good purpose, when and as long as the victim is a microbial pathogen. Sulphur drugs also find applications as antifungal ointments to fight against skin infections.

  • 出版日期2015