A selective transformation of flavanones to 3-bromoflavones and flavones under microwave irradiation

作者：Zhou ZZ; Zhao PL; Huang W; Yang GF^*

来源：Advanced Synthesis & Catalysis, 2006, 348(1-2): 63-67.

DOI：10.1002/adsc.200505223

• 3-bromoflavones
• N-bromosuccinimide
• flavanones
• flavones
• microwave irradiation

This paper presents the first report of a highly selective transformation of flavanones to 3-bromoflavones or flavones by microwave irradiation of the corresponding flavanone reactants and N-bromosuccinimide (NBS) in the presence of a catalytic amount of 2,2'-azobis(isobutyronitrile) (AIBN). The combination of good to excellent yields, shorter reaction time (10 min), and high levels of functional group compatibility make this an attractive synthetic approach to 3-bromoflavones and flavones.

• 出版日期2006-1
• 单位华中师范大学