Mitochondria-targeted fluorescent thermometer monitors intracellular temperature gradient

作者:Arai Satoshi; Suzuki Madoka; Park Sung Jin; Yoo Jung Sun; Wang Lu; Kang Nam Young; Ha Hyung Ho; Chang Young Tae*
来源:Chemical communications, 2015, 51(38): 8044-8047.
DOI:10.1039/c5cc01088h

摘要

Intracellular thermometry at the microscopic level is currently a hot topic. Herein we describe a small molecule fluorescent thermometer targeting mitochondria (Mito thermo yellow). Mito thermo yellow successfully demonstrates the ability to monitor the intracellular temperature gradient, generated by exogenous heating, in various cells.

  • 出版日期2015