A simple protocol for the preparation of beta-enamino ketones catalyzed by NbOPO4 under solvent free conditions

作者：Wodtke Felipe; Xavier Fernando R; Mendes Samuel R; de Oliveira Alfredo R M; Gariani Rogerio A^*

来源：Tetrahedron Letters, 2017, 58(3): 231-234.

DOI：10.1016/j.tetlet.2016.12.019

• Solvent-free
• 1,3-Dicarbonyl compounds
• Niobium oxide phosphate
• beta-Enamino esters
• beta-Enaminones

A novel application of the highly stable niobium oxide phosphate (NbOPO4) as an efficient catalyst for the synthesis of beta-enamino ketones under solvent-free conditions is described. This protocol, exhibits attractive yields, short reaction periods, lower loading of catalyst and high chemoselectivity.

• 出版日期2017-1-18