Direct Access to Polyisocyanide Screw Sense Using Vibrational Circular Dichroism

作者：Schwartz Erik; Domingos Sergio R; Vdovin Alexander; Koepf Matthieu; Buma Wybren Jan; Cornelissen Jeroen J L M^*; Rowan Alan E; Nolte Roeland J M; Woutersen Sander

来源：Macromolecules, 2010, 43(19): 7931-7935.

DOI：10.1021/ma101601e

We show that the screw sense of polyisocyanide helices can be determined in a simple manner from the vibrational circular dichroism (VCD) of their CN-stretching mode. The relation between VCD and molecular structure is obtained using the coupled-oscillator approximation. It is shown that since the C=N groups point approximately radially outward from the helical axis, the CN-stretch region of the VCD spectrum of a polyisocyanide helix consists of a single couplet, the sign of which is directly related to the screw sense of the helix. We use this method to determine the screw sense of poly(R)-2-isocyanooctane and poly(S)-2-isocyanooctane from their VCD spectrum.

• 出版日期2010-10-12