ALTERED GENTAMICIN SERUM CONCENTRATIONS IN OBESE PEDIATRIC PATIENTS

作者:Choi Jamie J*; Moffett Brady S; McDade Erin J; Palazzi Debra L
来源:Pediatric Infectious Disease Journal, 2011, 30(4): 347-349.
DOI:10.1097/INF.0b013e3181ff023e

摘要

We performed a retrospective case-cohort study of 50 obese pediatric patients aged 2 to 18 years who received scheduled gentamicin therapy, with serum peak and trough concentrations measured. Obese pediatric patients had significantly higher gentamicin serum peak and trough concentrations despite receiving significantly lower mg/kg of actual body weight doses of gentamicin.

  • 出版日期2011-4