Development of visible and NIR imaging equipment for small animals with smart pad

作者：Eum Nyeon Sik; Han Jung Hyun; Seong Ki Woong; Lee Jong Ha; Park Hee Joon^*

来源：Bio-medical Materials and Engineering, 2014, 24(6): 3033-3041.

DOI：10.3233/BME-141124

• Visible/NIR image
• animal imaging
• fluorescence
• mobile-based
• merged image

The portable visible and near-infrared (NIR) imaging equipment for a pre-clinical test with small animals was designed and developed in this paper. The developed equipment is composed of a CCD camera, a focusing lens, an objective lens, a NIR band pass filter and a NIR filter driving motor. An NIR ray is mainly used for imaging equipment because it has high light penetration depth in biological tissue. Therefore, NIR fluorescent agents are available for chemical conjugation to targeting molecules in vivo. This equipment can provide a visible image, NIR image and merged image simultaneously. A communication system was specifically established to check obtained images through a smart pad in real time. It is less dependent on space and time than the conventional system.

• 出版日期2014