Parental support buffers the association of depressive symptoms with cortisol and C-reactive protein during adolescence

作者：Guan Shu Sha Angie^*; Bower Julienne E; Almeida David M; Cole Steven W; Dahl Ronald E; Irwin Michael R; Seeman Teresa E; McDade Thomas; Fuligni Andrew J

来源：Brain, Behavior, and Immunity, 2016, 57: 134-143.

DOI：10.1016/j.bbi.2016.03.007

• Depressive symptoms
• Social support
• Inflammation
• Cortisol

Social experiences can affect the relationship between depression and physical health. The current study examined how social support from parents and friends may moderate the association of depressive symptoms with hypothalamic-pituitary-adrenal (HPA) axis activity and C-reactive protein among adolescents (N = 316, M-age = 16.40, SD =.74; 57% female) from diverse ethnic backgrounds (23.1% Asian, 29.1% European, 41.8% Latino, and 6.0% other backgrounds). Results indicated that parent support, but not friend support, moderated the link between depressive symptoms and both total daily cortisol output (a measure HPA activity) and C-reactive protein (a marker of inflammation). These patterns did not differ by ethnicity. Overall, the study highlights the continued, and perhaps accumulated, importance of parents during adolescence despite increasing needs for autonomy from and exploration outside of the family unit.

• 出版日期2016-10
• 单位西北大学