A Hyperelastic Constitutive Law for Aortic Valve Tissue

作者：May Newman Karen^*; Lam Charles; Yin Frank C P

来源：Journal of Biomechanical Engineering, 2009, 131(8): 081009.

DOI：10.1115/1.3127261

• biological tissues
• biomechanics
• cardiology
• elasticity
• patient treatment
• stress-strain relations

The objective of the present study was to perform biaxial testing and apply constitutive modeling to develop a strain energy function that accurately predicts the material behavior of the aortic valve leaflets. Ten leaflets from seven normal porcine aortic valves were biaxially stretched in a variety of protocols and the data combined to develop and fit a strain energy function to describe the material behavior. The results showed that the nonlinear anisotropic behavior of the aortic valve is well described by a strain energy function of two strain invariants, which uses only three coefficients to accurately predict the stress-strain behavior over a wide range of deformations. This structurally-motivated constitutive law has many applications, including computational modeling for clinical and engineering valve treatments.

• 出版日期2009-8