Ankylosing spondylitis kyphosis surgical correction postoperative evaluation via SRS-22 domain investigation

作者：Zhang, Hao; Zhang, XueSong^*; Hu, Fanqi; Hu, Wenhao; Wang, Yao; Hao, Yongyu

来源：Journal of Orthopaedic Surgery and Research, 2018, 13(1): 5.

DOI：10.1186/s13018-017-0699-4

• Scoliosis Research Society-22 (SRS-22)
• Ankylosing spondylitis kyphosis
• Pedicle subtraction osteotomy
• Activity
• Health-related quality of life (HRQOL)

Background: The SRS-22 is used to evaluate clinical outcomes in ankylosing spondylitis kyphosis patients. This study aimed to investigate the relationship between Scoliosis Research Society-22 (SRS-22) domains and satisfaction with management in patients who underwent surgical correction for ankylosing spondylitis kyphosis. The relationship between patient satisfaction and SRS-22 domain scores will feedback abundant information of therapeutic effect and significance for treatment guidance.
Methods: In this work, 106 patients with ankylosing spondylitis kyphosis at a single institution, who underwent posterior spinal fusion of five levels or more to the sacrum, completed SRS-22 evaluation preoperatively and followed up for a minimum of 2-year postoperation. Wilcoxon tests were performed to compare preoperative with 2-year postoperative scores. Spearman correlations were investigated to evaluate associations between the 2-year treatment satisfaction and therapeutic effect in SRS-22 domain scores.
Results: There were 12 females and 94 males with mean BMI of 16.4 kg/m(2) and at the mean age of 46.3 years. All of the primary surgeries were treatments performed with mean follow-up of 26 months. A statistical improvement between paired pre- and 2-year postoperative SRS-22 domain scores and most radiographical parameters, commonly P <= 0.05, was designed and implemented. The majority of patients gave SRS-22 satisfaction score with 3.0 or more (88.5%) or 4.0 or more (68.8%), which are consistent with the moderate ceiling effect. Spearman coefficient correlations between the SRS-22 domain scores and patient satisfaction were all statistically significant, and they were from low to strong: [Mental (0.30), Activity (0.71), Pain (0.25), and Appearance (0.40)]. Furthermore, correlations for all radiographical and operative parameters were from low to strong.
Conclusion: SRS-22 Activity domain correlates strongest with patient satisfaction in ankylosing spondylitis kyphosis patients who have undergone surgical correction at 2-year follow-up.

• 出版日期2018-1-9
• 单位中国人民解放军总医院