Molecular cloning, characterization and expression of miR-15a-3p and miR-15b-3p in dairy cattle

作者：Li, Zhixiong; Zhang, Huilin; Song, Ning; Wang, Hongliang; Chen, Ling; Zhai, Mengxing; Liu, Xiaolin^*

来源：Molecular and Cellular Probes, 2014, 28(5-6): 255-258.

DOI：10.1016/j.mcp.2014.06.003

• Dairy cattle
• Mastitis
• miR-15a-3p
• miR-156-3p
• Stem-loop qPCR

MicroRNA (miRNA) plays an important role in modulating immune responses. We identified miR-15a-3p and miR-15b-3p which were immune related in bovine. Fourteen potential target genes were predicted. Both miR-15a-3p and miR-15b-3p showed significant differential expression patterns in healthy and mastitis infected cattle (P < 0.01). Expression patterns of the two miRNAs provide important information on the relationships between mastitis and miRNA expression.

• 出版日期2014-12
• 单位西北农林科技大学