A modular trigger for the development of selective superoxide probes

作者：Yu, Zuo Hang; Chung, Clive Yik-Sham; Tang, Fung Kit; Brewer, Thomas F.; Au-Yeung, Ho Yu^*

来源：Chemical Communications, 2017, 53(72): 10042-10045.

DOI：10.1039/c7cc05405j

• ON FLUORESCENT-PROBE
• IN-VIVO
• LIVING CELLS
• NITRIC-OXIDE
• LIVE CELLS
• COPPER
• DEATH
• MECHANISM
• DISEASE
• COMPLEX

We report here a new bioinspired copper-based strategy of superoxide sensing and the development of sensitive (490-fold fluorescence turn-on) and selective superoxide probes for imaging variations in the endogenous superoxide level in various live mammalian cells (HEK293T, HeLa and A431).

• 出版日期2017-9-16
• 单位香港大学; 香港中文大学