Allele frequencies of 23 autosomal short tandem repeat loci in the Philippine population

作者：Rodriguez Jae Joseph Russell Beltran; Salvador Jazelyn M; Calacal Gayvelline C; Laude Rita P; De Ungria Maria Corazon A^*

来源：Legal Medicine, 2015, 17(4): 295-297.

DOI：10.1016/j.legalmed.2015.02.005

• Short tandem repeat
• Allele frequency
• Population database
• Philippines
• PowerPlex (R) 21 system
• Verifiler (TM) direct PCR amplification kit

We characterized diversity and forensic descriptive parameters of 23 autosomal SIR loci (CSF1PO, D13S317, D16S539, D5S818, D7S820, TPOX, D18S51, D21S11, D3S1358, D8S1179, FGA, TH01, vWA, D1S1656, D10S1248, D125391, D2S441, D22S1045, D19S433, D2S1338, D6S1043, Penta D and Penta E) among 167 unrelated Filipinos. The most variable autosomal SIR loci observed is Penta E (observed heterozygosity: 0.9222, match probability: 0.0167). Results reveal matching probability of 8.21 x 10(-28) for 23 autosomal SIR loci. This dataset for the Philippine population may now be used in evaluating the weight of DNA evidence for forensic applications such as in human identification, parentage/kinship testing, and interpretation of DNA mixtures.

• 出版日期2015-7