Addition-versus-Oxygenative Cleavage: Two Contradictory Reactivities in the Reaction of N-Benzyl-4-pentenylamine Catalyzed by Colloidal Nanogold under Aerobic Conditions

作者：Kitahara Hiroaki; Sakurai Hidehiro^*

来源：Chemistry Letters, 2012, 41(10): 1328-1330.

DOI：10.1246/cl.2012.1328

Gold nanoclusters stabilized by a hydrophilic polymer, poly(N-vinyl-2-pyrrolidone), (Au:PVP) catalyze two contradictory types of the reaction from N-benzyl secondary amines with unactivated alkenes in EtOH under basic conditions. One is an intramolecular addition reaction that also starts from N-sulfonylamine or primary amine as previously reported. The other involves the oxygenative cleavage of alkene, giving the corresponding gamma-lactam compound.

• 出版日期2012-10-5