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An introduction to molecular replacement
作者:Evans Philip
*
; McCoy Airlie
来源:
Acta Crystallographica Section D-Biological Crystallography
, 2008, 64: 1-10.
DOI:10.1107/S0907444907051554
molecular replacement is fundamentally a simple trial-anderror
method of solving crystal structures when a suitable
related model is available. The underlying simplicity of the
method is often obscured by the mathematical trickery
required to make the searches computationally tractable. This
introduction sketches the essential issues in molecular
replacement without going into technical details. General
search strategies are discussed and the alternative Patterson
and likelihood approaches are outlined.
出版日期
2008-1
单位
河北医科大学
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