Detection of human parechoviruses in children with gastroenteritis in South Korea

作者：Han Tae Hee; Kim Cheol Hwan; Park Sang Hun; Chung Ju Young^*; Hwang Eung Soo

来源：Archives of Virology, 2011, 156(8): 1471-1475.

DOI：10.1007/s00705-011-0995-y

• Human parechovirus
• Acute gastroenteritis
• Children

Human parechoviruses (HPeVs) are associated with gastroenteritis (GE), although their etiologic role is uncertain. The purpose of this study was to detect HPeVs in children with GE in Korea. A total of 348 stool samples that were negative for common enteric viruses were screened for HPeV using RT-PCR. Of the 348 stool samples, seven (2.0%) were positive for HPeV. Five Korean strains belonged to HPeV-1, and two strains belonged to HPeV-4. Four Korean HPeV-1 strains clustered with strain 7555312 and the other HPeV-1 strain clustered with the BNI-788St strain. Two HPeV-4 strains showed discordant phylogenic relationships in the 3D gene, suggesting that recombination had occurred. This is the first study reporting the detection of HPeVs in children with GE in Korea.

• 出版日期2011-8