A novel Synthesis of 3-Amino-1-Adamantanemethanol

作者:Cai Lu*; Guo Jianwei; Liu Sa; Yang Chufen; Zhu Hua; Peng Jinping
来源:International Conference on Chemical Engineering and Advanced Materials, Changsha, 2011-05-28 To 2011-05-30.
DOI:10.4028/www.scientific.net/AMR.233-235.225

摘要

3-amino-1-adamantanemethanol was synthesized from adamantane carboxylic acid following the procedures of Ritter reaction, hydrolysis, neutralization and reduced reaction without the participation of bromine. The total yield of 3-amino-1-adamantanemethanol was 43%. The structure of the target compound was characterized by elemental analysis, IR, MS, 1HNMR,etc. In addition, the possible reaction mechanisms was proposed.