A new steroidal saponin, yuccalan, from the leaves of Yucca smalliana

作者：Jin Yu Lan; Kuk Ju Hee; Oh Kyung Taek; Kim Young Ju; Piao Xiang Lan; Park Ro Dong^*

来源：Archives of Pharmacal Research, 2007, 30(5): 543-546.

DOI：10.1007/BF02977645

• antimicrobial activity
• Yucca smalliana
• 3-O-beta-D-glucopyranosyl-(1 -&gt
• 6)-beta-D-glucopyranosyl-(3 beta, 5 alpha, 6 alpha
• 25S)-spirostan-3,6,27-triol
• Yuccalan

An extract of the leaves of Yucca smalliana Fern. (Agavaceae) showed potential antimicrobial activity. Employing a bioassay linked fractionation method, one of the active principles, namely yuccalan, was isolated as a new steroidal saponin. The structure of the new steroidal saponin was elucidated as 3-O-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranosyl-(3 beta, 5 alpha, 6 alpha, 25S)-spirostan-3,6,27-triol (1) using various spectroscopic techniques, including IR, MS, 1D and 2D H-1-NMR, and C-13-NMR. The purified yuccalan showed antifungal activities against both Rhizoctonia solani and Fusarium oxysporum.

• 出版日期2007-5
• 单位北京大学