Macrostachyols A-D, new oligostilbenoids from the roots of Gnetum macrostachyum

作者：Sri in Piyawit; Sichaem Jirapast; Siripong Pongpun; Tip pyang Santi^*

来源：Fitoterapia, 2011, 82(3): 460-465.

DOI：10.1016/j.fitote.2010.12.008

• Gnetaceae
• Gnetum macrostachyum
• Oligostilbenoids
• Cytotoxicity

Four new oligostilbenes, macrostachyols A-D (1-4) along with six known stilbenoids (5-10), were isolated from the roots of Gnetum macrostachyum. These compounds were also evaluated for their cytotoxicity towards HeLa and KB cell lines. Only compound 4 showed the significant cytotoxicity to HeLa cells with IC50 value of 4.13 mu M.

• 出版日期2011-4