Addition/elimination reactions of ethylsulfonyl pyridines: stereoselective synthesis of vinylpyridine allylic alcohols

作者：O'Neil Gregory W^*; Drake Nathan D; Storvick Jennifer M

来源：Tetrahedron Letters, 2013, 54(7): 715-717.

DOI：10.1016/j.tetlet.2012.12.049

• Pyridine
• Sulfone
• Addition/elimination
• Stereoselective
• Heterocycle

2-(Phenylsulfonyl)ethyl pyridines can be coupled with aldehydes leading directly to sulfone-eliminated vinylpyridine allylic alcohols. These products are obtained in good yield and with high levels of stereocontrol.

• 出版日期2013-2-13