A new access to 3-halo-3,3-difluoropropanoic acid derivatives via fluorine-halogen exchange reaction of silyl enolates of 3,3,3-trifluoropropanoic acid derivatives

作者：Shimada Taichi; Konno Tsutomu; Ishihara Takashi^*

来源：Chemistry Letters, 2007, 36(5): 636-637.

DOI：10.1246/cl.2007.636

On the treatment of silyl enolates derived from N-(3,3,3-trifluoropropanoyl)oxazolidinones with 2.0 equiv. of titanium(IV) halide at -20 degrees C for 2 h, a novel fluorine-halogen exchange reaction occurred efficiently to give 3-halo-3,3-difluoropropanoic imides in high yields.

• 出版日期2007-5-5