A highly selective and sensitive fluorescein-based chemodosimeter for Hg2+ ions in aqueous media

作者：Yang Xiao Feng^*; Li Yu; Bai Quan

来源：Analytica Chimica Acta, 2007, 584(1): 95-100.

DOI：10.1016/j.aca.2006.11.015

• Hg2+
• fluorescein
• chemodosimeter
• fluorimetry

A new fluorescein-based chemodosimeter (II) for Hg2+ ion was designed and synthesized, and it displayed excellent selective and sensitive toward Hg2+ ion over other commonly metal ions in aqueous media. II was a colorless, non-fluorescent compound. Upon addition of Hg2+ to the solution of II, the thiosemicarbazide moiety of II would undergo an irreversible desulfurization reaction to form its corresponding oxadiazole (IV), a colorful and fluorescent product. During this process, the spirocyclic ring of II was opened, causing instantaneous development of visible color and strong fluorescence emission in the range of 500-600 nm. Based on the above mechanism, a fluorogenic Hg2+-selective chemodosimeter was developed. The fluorescence increase is linearly with Hg2+ concentration up to 1.0 mu mol L-1 with a detection limit of 8.5 x 10(-10) mol L-1 (3 sigma). Compared with the rhodamine-type chemodosimeter, II is more stable in aqueous media and exhibits higher sensitivity toward Hg2+. The findings suggest that II will serve as a practical chemodosimeter for rapid detection of Hg2+ concentrations in realistic media.

• 出版日期2007-2-12
• 单位西北大学