An Efficient ZnO-Nanoparticle-Catalyzed Regio- and Chemoselective Synthesis of Novel Functionalized 4H-Chromenes in Aqueous Medium

作者：Rao Lenka Chandrasekhara; Kumar Nandigama Satish; Bheeram Vema Reddy; Hemambika Sadasivuni; Mukkamala Sarathchandra Babu

来源：ChemistrySelect, 2018, 3(26): 7485-7489.

DOI：10.1002/slct.201800503

• catalysis
• 4H-chromenes
• cyclic diketones
• 3-methyl-2-pyrazolin-5-one
• ZnO nanoparticle

ZnO nanoparticles (ZnO NPs) catalyzed synthesis of novel 4H-chromene hemiacetals with 3-methyl-2-pyrazolin-5-one and cyclic 1,3-diketone with high regioselectivity in aqueous medium has been demonstrated. This method is applicable to diverse substituted chromene hemiacetals and different functionalized 1,3-diketones. All these reactions proceeded smoothly, and the products were obtained in good to excellent yields. The catalyst could be recycled and reused up to 5 cycles without any loss of efficiency.

• 出版日期2018-7-13