An efficient synthesis of dialkyl 2-((alkylimino)methylene)-3-(2-methyl-4-oxoquinolin-1(4H)-yl)succinate through three component reaction of alkyl isocyanides, dialkylacetylenedicarboxylate and 2-methyl-4-hydroxyquinoline

作者：Mohtat Bita^*; Matinfar Mahnaz; Rezazadeh Somayeh; Djahaniani Hoorieh

来源：Indian Journal of Chemistry - Section B: Organic and Medicinal Chemistry , 2013, 52(9): 1232-1235.

• Ketenimines
• alkyl isocyanides
• acetylenic esters
• 2-metyl-4-hydroxyquinoline
• multi-component reaction

The 1:1 reactive intermediates generated by the addition of alkyl isocyanides to dialkylacetylenedicarboxylatesare trapped by 2-methyl-4-hydroxyquinoline to yield highly functionalized ketenimines.

• 出版日期2013-9