An Overview of Tissue Engineering as an Alternative for Toxicity Assessment

作者:Garrod Mathew; Chau David Y S
来源:Journal of Pharmacy and Pharmaceutical Sciences, 2016, 19(1): 31-71.
DOI:10.18433/J35P6P

摘要

Tissue engineering is a multidisciplinary field that combines aspects of biology, material sciences, engineering and medicine - the ultimate goal being able to fabricate replacement tissues and/or organs for an ageing population. However, parallel to this milestone, is the exploitation of the biomimetic constructs as feasible alternatives to in vivo/ex vivo toxicity testing models due to their accurate representation of innate tissue and organs. Herein, we summarise a range of concepts within tissue engineering with a particular emphasis on biological material selection and implications to animal testing.

  • 出版日期2016