摘要

The compound ZKY-1 with a D-pi-A structure was designed and synthesized in four steps. It undergoes complexation with a tetravalent zirconium ion and the complex can be used for the detection of phosphorylated proteins. The detection limit is estimated to be 100 nm in vitro. The successful detection of phosphorylated proteins in placental tissue samples indicates that this probe holds great potential for clinical diagnosis.

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