A novel strategy to evaluate the degradation of quantum dots: identification and quantification of CdTe quantum dots and corresponding ionic species by CZE-ICP-MS

作者：Meng, Peijun; Xiong, Yamin; Wu, Yingting; Hu, Yue; Wang, Hui; Pang, Yuanfeng; Jiang, Shuqing; Han, Sihai; Huang, Peili^*

来源：Chemical communications, 2018, 54(42): 5342-5345.

DOI：10.1039/c8cc01974f

• PLASMA-MASS SPECTROMETRY
• IN-VIVO DISTRIBUTION
• NANOPARTICLES
• PHARMACOKINETICS
• CHROMATOGRAPHY
• SEPARATION
• PROTEIN
• CELLS
• GOLD

In view of the significance and urgency of the speciation analysis of quantum dots (QDs) and their degradation products for clarifying their degradation rules and toxicity mechanisms, a method for the identification and quantification of CdTe QDs and corresponding ionic species in complex matrices was developed using capillary zone electrophoresis (CZE) coupled to inductively coupled plasma-mass spectrometry (ICP-MS). The quality assessment of commercial CdTe QDs and serum pharmacokinetics of synthesized CdTe QDs in rats were successfully undertaken using the developed CZE-ICP-MS method.

• 出版日期2018-5-25
• 单位内蒙古科技大学包头医学院; 首都医科大学; 河南大学; 内蒙古科技大学