Non-linear effects in acyclic amino acid-catalyzed direct asymmetric aldol reactions

作者：Dziedzic Pawel; Zou Weibiao; Ibrahem Ismail; Sunden Henrik; Cordova Armando^*

来源：Tetrahedron Letters, 2006, 47(37): 6657-6661.

DOI：10.1016/j.tetlet.2006.06.167

Non-linear effects were observed in acyclic amino acid-catalyzed direct asymmetric intermolecular aldol reactions. The non-linear effects are due to the equilibrium solid-liquid phase behavior of amino acids. The results suggest that the phase behavior of amino acids linked to asymmetric catalysis may have implications to the evolution of homochirality.

• 出版日期2006-9-11