Differential roles of human striatum and amygdala in associative learning

作者:Li Jian; Schiller Daniela; Schoenbaum Geoffrey; Phelps Elizabeth A; Daw Nathaniel D
来源:Nature Neuroscience, 2011, 14(10): 1250-1252.
DOI:10.1038/nn.2904

摘要

Although the human amygdala and striatum have both been implicated in associative learning, only the striatum';s contribution has been consistently computationally characterized. Using a reversal learning task, we found that amygdala blood oxygen level-dependent activity tracked associability as estimated by a computational model, and dissociated it from the striatal representation of reinforcement prediction error. These results extend the computational learning approach from striatum to amygdala, demonstrating their complementary roles in aversive learning.

  • 出版日期2011-10