Highly Enantioselective Carbonyl-ene Reactions Catalyzed by In(III)-PyBox Complex

作者:Zhao Jun Feng; Tsui Hoi Yan; Wu Pei Jia; Lu Jun; Loh Teck Peng*
来源:Journal of the American Chemical Society, 2008, 130(49): 16492-+.
DOI:10.1021/ja807501a

摘要

A highly enantioselective carbonyl-ene reaction catalyzed by In(III)-pybox is described. Both 1, 1-disubstituted alkenes and 1,1,2-trisubstituted alkenes proceeded smoothly to give the ene products in high yields up to 97% and with excellent diastereoselectivity and enantioselectivities up to > 99:1 and 99%, respectively.

  • 出版日期2008-12-10
  • 单位南阳理工学院