摘要
Investigation of the unexpected photo-instability of 2,6-sulfonamide-substituted derivatives of the boron dipyrromethene (BODIPY) fluorophore led to the discovery of a photoreaction accompanied by multiple bond scissions. We characterized the photoproducts and utilized the photoreaction to design a caged -aminobutyric acid (GABA) derivative that can release GABA upon irradiation in the visible range (>450nm). This allowed us to stimulate neural cells in mouse brain slices.
- 出版日期2016-7-1