Dynamics under the Telomeric Bridge

作者:Pisano, Sabrina; Gilson, Eric; Giraud-Panis, Marie-Josephe*
来源:Molecular Cell, 2017, 68(4): 643-644.
DOI:10.1016/j.molcel.2017.11.005

摘要

In this issue of Molecular Cell, Kim et al. (2017) have studied the structure and organization of the shelterin protein complex protecting telomeres in Schizosaccharomyces pombe and humans and discovered an allosteric structural transition that drives the formation of the shelterin complex and participates in telomere length regulation.