Antimicrobial activity of crude epicarp and seed extracts from mature avocado fruit (Persea americana) of three cultivars

作者：Chia Teck Wah Raymond^*; Dykes Gary A

来源：Pharmaceutical Biology, 2010, 48(7): 753-756.

DOI：10.3109/13880200903273922

• Antimicrobial
• avocado cultivar
• epicarp
• extracts
• seed

The epicarp and seed of Persea Americana Mill. var. Hass (Lauraceae), Persea Americana Mill. var. Shepard, and Persea americana Mill. var Fuerte cultivars of mature avocados (n=3) were ground separately and extracted with both absolute ethanol and distilled water. Extracts were analyzed for antimicrobial activity using the microtiter broth microdilution assay against four Gram-positive bacteria, six Gram-negative bacteria, and one yeast. Antimicrobial activity against two molds was determined by the hole plate method. The ethanol extracts showed antimicrobial activity (104.2-416.7 mu g/mL) toward both Gram-positive and Gram-negative bacteria (except Escherichia coli), while inhibition of the water extracts was only observed for Listeria monocytogenes (93.8-375.0 mu g/mL) and Staphylococcus epidermidis (354.2 mu g/mL). The minimum concentration required to inhibit Zygosaccharomyces bailii was 500 mu g/mL for the ethanol extracts, while no inhibition was observed for the water extracts. No inhibition by either ethanol or water extracts was observed against Penicillium spp. and Aspergillus flavus.

• 出版日期2010-7