Do Patients With Parkinson's Disease Exhibit Reduced Cheating Behavior? A Neuropsychological Study

作者：Abe Nobuhito; Kawasaki Iori; Hosokawa Hiroaki; Baba Toru; Takeda Atsushi

来源：Frontiers in Neurology, 2018, 9: 378.

DOI：10.3389/fneur.2018.00378

• honesty
• morality
• Parkinson's disease
• personality
• reward

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by loss of dopamine neurons Since a seminal report was published in the early twentieth century, a growing body of literature has suggested that patients with PD display characteristic personality traits, such as cautiousness and inflexibility Notably, PD patients have also been described as "honest," indicating that they have a remarkable tendency to avoid behaving dishonestly In this study, we predicted that PD patients show reduced cheating behavior in opportunities for dishonest gain due to dysfunction of the dopaminergic reward system Thirty two PD patients without dementia and 20 healthy controls (HC) completed an incentivized prediction task where participants were rewarded based on their self-reported accuracy, affording them the opportunity to behave dishonestly Compared with HC, PD patients showed significantly lower accuracy in the prediction task Furthermore, the mean accuracy of PD patients was virtually equivalent to the chance level These results indicate that PD patients exhibit reduced cheating behavior when confronted with opportunities for dishonest gain.

• 出版日期2018-5-24