An efficient iron-catalyzed S-arylation of aryl and alkylthiols with aryl halides in the presence of water under aerobic conditions

作者：Sindhu K S; Thankachan Amrutha P; Thomas Anns Maria; Anilkumar Gopinathan^*

来源：Tetrahedron Letters, 2015, 56(34): 4923-4926.

DOI：10.1016/j.tetlet2015.06.087

• C-S coupling
• Iron catalysis
• Green chemistry
• Thioetherification
• Cross coupling

In this study, an environmentally benign FeCl3 center dot 6H(2)O/L-proline catalytic system in the presence of TBAB was employed as a catalyst for the coupling reactions of aryl halides with aryl and alkyl thiols in water under aerobic conditions. The versatility, low cost, and environmental friendliness, in combination with high yields, makes the procedure noteworthy. This protocol offers a simple and efficient thioetherification method for aryl halides.

• 出版日期2015-8-19