Antibacterial effects of cinnamon oil against carbapenem resistant nosocomial Acinetobacter baumannii and Pseudomonas aeruginosa isolates

作者：Kaskatepe Banu^*; Kiymaci Merve Eylul; Suzuk Serap; Erdem Sinem Aslan; Cesur Salih; Yildiz Sulhiye

来源：Industrial Crops and Products, 2016, 81: 191-194.

DOI：10.1016/j.indcrop.2015.11.058

• Acinetobacter baumannii
• Antibacterial activity
• Cinnamon oil
• Pseudomonas aeruginosa
• GC
• GC/MS

Widespread existence of drug-resistant pathogens poses a threat to the successful treatment of bacterial diseases and increases the need for new antibacterial agents. Natural products are the basic source of antibacterial therapeutic agents for now, and will remain so in the future. Therefore, the aim of this study was to determine the antibacterial activity of cinnamon oil against carbapenem-resistant nosocomial isolates of Acinerobacter baumannii (111) and Pseudomonas aeruginosa (136). The essential oil composition of cinnamon oil was analyzed by GC, GC/MS and the antimicrobial effect of cinnamon oil was determined by disk diffusion method. The observed zone diameters were compared with carbapenem breakpoints (CLSI standard) and it was found that only one of the P. aeruginosa isolates was within resistance limits. Thus, cinnamon oil has antimicrobial activity with potential use as an antimicrobial agent in the pharmaceutical industry and an additive in the food industry.

• 出版日期2016-3