Atom-Economical Chemoselective Synthesis of 1,4-Diynes and Polysubstituted Furans/Pyrroles from Propargyl Alcohols and Terminal Alkynes

作者：Wang Tao; Chen Xin liang; Chen Li; Zhan Zhuang ping^*

来源：Organic Letters, 2011, 13(13): 3324-3327.

DOI：10.1021/ol201054z

Under different conditions, the reaction of propargyl alcohols and terminal alkynes leads to the selective formation of 1,4-diynes and polysubstituted furans/pyrroles. Water is the only byproduct in the selective synthesis of 1,4-diynes and pyrroles, and the strategy for the furan synthesis is of 100% atom economy.

• 出版日期2011-7-1
• 单位厦门大学