Dumbbell-like PtPd-Fe3O4 Nanoparticles for Enhanced Electrochemical Detection of H2O2

作者：Sun Xiaolian; Guo Shaojun; Liu Yi; Sun Shouheng^*

来源：Nano Letters, 2012, 12(9): 4859-4863.

DOI：10.1021/nl302358e

• PtPd alloy
• dumbbell nanoparticles
• electrocatalysis
• H2O2 detection

Dumbbell-like PtxPd100-x-Fe3O4 nanoparticles (NPs) were synthesized and studied for electrocatalytic reduction and sensing of H2O2. In 0.1 M phosphate buffered saline (PBS) solution, the 4-10 nm PtxPd100-x-Fe3O4 NPs showed the Pt/Pd composition-dependent catalysis with Pt48Pd52-Fe3O4 NPs having the best activity. The Pt48Pd52-Fe3O4 NPs were tested for H2O2 detection, and their H2O2 detection limit reached 5 nM, which was suitable for monitoring H2O2 generated from Raw 264.7 cells. These dumbbell-like PtPd-Fe3O4 NPs are the most sensitive probe ever reported and can be used to achieve real-time quantitative detection of H2O2 in biological environment for biological and biomedical applications.

• 出版日期2012-9