Anterior Reconstruction With Nano-hydroxyapatite/polyamide-66 Cage After Thoracic and Lumbar Corpectomy

作者：Yang, Xi; Song, Yueming^*; Liu, Limin; Liu, Hao; Zeng, Jiancheng; Pei, Fuxing

来源：Orthopedics, 2012, 35(1): E66-E73.

DOI：10.3928/01477447-20111122-10

• TITANIUM MESH CAGES
• HEALTH SURVEY SF-36
• RADIOLOGIC ASSESSMENT
• SURGICAL EXPLORATION
• INTERBODY FUSION
• CERVICAL-SPINE
• COMPOSITES
• ALLOGRAFTS
• FRACTURES

Cages are used to regain stability of the anterior spinal column following vertebrectomy, which could prevent significant donor-site morbidity from the iliac autograft harvesting and the risk of disease transmission associated with the allograft. The hollow, porous, cylindrical nano-hydroxyapatite/polyamide 66 (n-HA/PA66) cage is a new nonmetallic cage device made by combining nano-hydroxyapatite with polyamide 66. Few studies have examined its effectiveness and outcomes over a follow-up >2 years. @@@ We retrospectively studied 51 consecutive patients with acute traumatic thoracic or lumbar burst fracture who underwent anterior reconstruction with the n-HA/PA66 cage following single-level corpectomy. Radiologic parameters (radiographs and 3-dimensional computed tomography scans) preoperatively and at 1 week and >2 years postoperatively, as well as clinical outcome parameters (SF-36 scores), were analyzed. Mean kyphosis correction in the segment within the cage was 11.8 degrees +/- 7.1 degrees, and mean loss of correction at last follow-up was 1.9 degrees +/- 2.1 degrees. Osseous fusion was achieved in 90.2% of patients, and severe cage subsidence (settling >2 mm) was observed in 19.6% of patients at final follow-up. Significant differences were found in 7 of 8 health dimensions of the SF-36 between neurologically intact patients and neurologically injured patients. Our clinical results indicate that the n-HA/PA66 cage is an effective device for reconstruction after anterior thoracic and lumbar vertebral resection, resulting in a high rate of successful osseous fusion and a low proportion of severe cage subsidence.

• 出版日期2012-1
• 单位四川大学