An Argonaute Protein Directs Nuclear Xrn2 Function

作者：Hasler Daniele; Meister Gunter^*

来源：Molecular Cell, 2012, 48(4): 485-486.

DOI：10.1016/j.molcel.2012.11.015

Argonaute proteins are the mediators of small RNA-guided gene silencing pathways. In this issue, Couvillion and coworkers (Couvillion et al., 2012) found an unexpected function for a Tetrahymena Argonaute protein: It forms a complex with tRNA fragments and is required for nuclear Xrn2 localization and function.

• 出版日期2012-11-30