A tri(potassium sulfonate) derivative of perchlorotriphenylmethyl radical (PTM) as a stable water soluble radical-scavenger of the hydroxyl radical more powerful than 5,5-dimethyl-1-pyrroline-N-oxide

作者：Antonio Mesa Juan; Chavez Sergei; Fajari Lluis; Lluis Torres Josep; Julia Luis

来源：RSC Advances, 2013, 3(25): 9949-9956.

DOI：10.1039/c3ra41499j

The tripotassium salt of tris(2,3,5,6-tetrachloro-4-hydroxysulfonylphenyl) methyl radical (3 K+ TSPTM3-) reacts in water with hydroxyl radical very fast with a rate constant (k = 2.4 x 10(11) M-1 s(-1)) much higher than that of the reaction of hydroxyl radical with the spin trap 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) (k = 3.4 x 10(9) M-1 s(-1)). The reaction affects the radical character of the molecule and is monitored by electron paramagnetic resonance (EPR). The hydroxyl radical scavenging is established by the characterization of the resulting water-soluble product as the dipotassium salt of 4-[ bis(2,3,5,6-tetrachloro-4-hydroxysulfonylphenyl) methylene]-2,3,5,6-tetrachlorocyclohexa-2,5-dien-1-one (2).

• 出版日期2013