科研之友
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摘要
Patients with type 2 diabetes mellitus (T2DM) often suffer from several comorbidities. However, there is a scarcity in representative data describing both the comorbidity status and drug therapy of German T2DM patients. The main objective of this analysis was to describe comorbidity status and drug-based therapy of patients with T2DM. In addition, the adequacy of the drug therapy for older patients was assessed. All analyses were done based on a claims data set provided by AOK Plus; the data set covered the years 2010-2012. In 5 different patient subgroups, as defined by the number of different medications these patients received, we reported the top 20 comorbidities and medications. For older patients aged at least 65 years, we assessed adequacy of medication for antidiabetic and antihypertensive medication based on the FORTA (Fit for the Aged) list. Included in the final data set were 403,360 patients with T2DM (mean age 72.1 years); 55.9% were women. The most frequently observed comorbidities were hypertension (91.3%) and lipid metabolism disorders (56.6%). In line with that, 93.9% of all T2DM patients received antihypertensive drugs. Based on the FORTA assessment, almost every sixth patient with T2DM, who was at least 65 years old, received a pharmacological treatment that should be avoided in this age group. In real life, German patients with T2DM suffer from several comorbidities that are treated with different medications. Pharmacological therapy of older patients can be improved in a substantial percentage of patients.
- 出版日期2017-3
