科研之友
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摘要
In order to obtain a novel prescription to treat scald, a new ointment was assessed. The ointment was made of pepsin soluble collagen (PSC), Bletilla striata polysaccharide (CBSP), lentinan, 1-octadecanol, dodecyl sodium sulfate, white vaseline, methyl hydroxybenzoate, propyl hydroxybenzoate, propylene glycol and distilled water. Experiment involving mice with their biochemical assays was used to evaluate the suitability of the ointment. The ointment which include by 1.5 g PSC, 1.5 g CBSP, 1.5 g lentinan, 20 g 1-octadecanol, 1.46 g dodecyl sodium sulfate, 23 g white vaseline, 0.025 g methyl hydroxybenzoate, 0.015 g propyl hydroxybenzoate, 11 g propylene glycol, and 40 g distilled water is optimal ointment. The scar outcomes rate all reach 100.00% in ointment group and model group. However, the ointment group of scar outcomes rate is higher than model group in the tenth day. The ointment 1, 2 and 3 group can significantly improve the activity of superoxide dismutase, increase the content of monoamine oxidase and reduce the content of malondialdehyde. The ointment had no influence on the body mass, the relative organ mass, blood hematology and serum biochemical indices of the mice. The results of the study indicated that the ointment can be used to treat scalds on mouse, increase the rate of the scar outcome and promote scald heal.
- 出版日期2015
- 单位江苏大学
