A new facile synthesis of 3-amidoindole derivatives and their evaluation as potential GSK-3 beta inhibitors

作者:Pews Davtyan Anahit; Tillack Annegret; Schmoele Anne Caroline; Ortinau Stefanie; Frech Moritz J; Rolfs Arndt*; Beller Matthias
来源:Organic and Biomolecular Chemistry, 2010, 8(5): 1149-1153.
DOI:10.1039/b920861e

摘要

3-Amidoindoles were synthesized from commercially available arylhydrazines and propargylamines over Zn-salt mediated one pot procedure in excellent regioselectivity and up to 94% yield.

  • 出版日期2010