A new dimeric resveratrol from the roots of Shorea roxburghii

作者：Patcharamun Winitra; Sichaem Jirapast; Siripong Pongpan; Khumkratok Suttira; Jong aramruang Jonkolnee; Tip pyang Santi^*

来源：Fitoterapia, 2011, 82(3): 489-492.

DOI：10.1016/j.fitote.2011.01.003

• Dipterocarpaceae
• Shorea roxburghii
• Roxburghiol A
• Cytotoxicity

A new resveratrol dimer, roxburghiol A (1) together with eleven known compounds were isolated from the roots of Shorea roxburghii. Their structures were identified on the basis of spectroscopic evidence and physicochemical properties. All isolated compounds were evaluated for their cytotoxicity (KB and HeLa cells). Compounds 8 and 9 showed potent cyrotoxicity against both KB and HeLa cell lines with IC(50) values of 6.5, 8.5 and 8.7, 10.1 mu g/mL, respectively.

• 出版日期2011-4