A Nonsymmetric Pincer-Catalyzed Suzuki-Miyaura Arylation of Benzyl Halides and Other Nonactivated Unusual Coupling Partners

作者：Ines Blanca; Moreno Isabel; SanMartin Raul^*; Dominguez Esther

来源：Journal of Organic Chemistry, 2008, 73(21): 8448-8451.

DOI：10.1021/jo8016633

The catalytic activity of a PCN-type palladium pincer complex is evaluated in the construction of C(sp(2))-C C(sp(2)) and C(sp(2))-C(sp(3)) bonds by Suzuki-Miyaura cross-couplings employing nontypical subs such as benzyl halides, alpha-haloenones, or alkylboronic acids as coupling partners. Most of the reported reactions are achieved in aqueous media, with all of the advantages implied.

• 出版日期2008-11-7