Cool-tip 10-mm Electrode Useful for Radiofrequency Ablation of Hepatocellular Carcinoma

作者：Wakui Noritaka^*; Iida Kazunari; Takayama Ryuji; Shiozawa Kazue; Takahashi Masayoshi; Ikehara Takashi; Nagai Hidenari; Watanabe Manabu; Ishii Koji; Sumino Yasukiyo

来源：Hepato-Gastroenterology, 2009, 56(96): 1585-1591.

• Hepatocellular carcinoma
• Radiofrequency ablation
• cool-tip 10mm electrode
• Local progression
• Two-step ablation method

Background/Aims: Whether a cool-tip 10mm electrode is useful for radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC) has not been established. Accordingly, the present study goal was to determine this electrode is indicated for RFA of HCC.
Methodology: This study was conducted with 30 HCC patients who were treated with a cool-tip 10mm electrode over a period of about 3 years. Ten had hypervascular HCC nodules and 20 had hypovascular HCC nodules; mean tumor diameter was 10.5+/-1.8mm. Patients underwent follow-up CT scans every 3 to 6 months to detect local progression.
Results: Of the 30 lesions, 4 (13.3%) showed local progression. Enhanced CT imaging of the four cases with local progression revealed that two had hypervascular HCC. The remaining two cases had hypovascular HCC.
Conclusions: The present study results suggest that, RFA with a cool-tip 10-mm electrode is indicated in cases of hypovascular HCC nodules if the lesion diameter is no more than 10mm. In addition, in order to avoid skin burns, only lesions at a depth of at least 16mm below the liver surface are suitable for this treatment. Because of its lesser invasiveness, the cool-tip 10-mm electrode appears to be more useful than other, more powerful, devices in patients with hepatic carcinoma.

• 出版日期2009-12