Does COPD have a clinically relevant impact on hearing loss? A retrospective matched cohort study with selection of patients diagnosed with COPD

作者：Kamenski Gustav^*; Bendova Jana; Fink Waltraud; Soennichsen Andreas; Spiegel Wolfgang; Zehetmayer Sonja

来源：BMJ Open, 2015, 5(11): e008247.

DOI：10.1136/bmjopen-2015-008247

Objectives: Chronic obstructive pulmonary disease (COPD) as a multisystemic disease has a measurable and biologically explainable impact on the auditory function detectable in the laboratory. This study tries to clarify if COPD is also a significant and clinically relevant risk factor for hearing impairment detectable in the general practice setting.
Design: Retrospective matched cohort study with selection of patients diagnosed with COPD.
Setting: 12 general practices in Lower Austria.
Participants: Consecutive patients >35 years with a diagnosis of COPD who consulted 1 of 12 singlehanded GPs in 2009 and 2010 were asked to participate. Those who agreed were individually 1:1 matched with controls according to age, sex, hypertension, diabetes, coronary heart disease and chronic heart failure.
Main outcome measures: Sensorineural hearing impairment as assessed by pure tone audiometry, answers of three questions concerning a self-perceived hearing problem, application of the whispered voice test and the score of the Hearing Inventory for the Elderly, Screening Version (HHIE-S).
Results: 194 patients (97 pairs of 194 cases and controls) with a mean age of 65.5 (SD 10.2) were tested. Univariate conditional logistic regression resulted in significant differences in the mean bone conduction hearing loss and in the total score of HHIES, in the multiple conditional regression model, only smoking (p < 0.0001) remained significant.
Conclusions: The results of this study do not support the hypothesis that there is an association between COPD and hearing impairment which, if found, would have allowed better management of patients with COPD.

• 出版日期2015